Green Chemistry Approaches in The Synthesis of Anti-Inflammatory Drug

Abstract

The overall work on the development of anti-inflammatory drug candidates has taken a new twist as green chemistry has been introduced in the aim of keeping the environment unharmed or impacted, even though the effectiveness of the drugs and dosage support the mention of efficacy and safety. This review article examines the recent developments on sustainable and environmentally friendly green processes in the synthesis of anti-inflammatory compounds both in relation to the animal trials and not the human ones. It includes review of topic of green solvents, biocatalysis, microwave-assisted synthesis, ionic liquids and other environmentally compatible strategies used during the preparation of pharmaceually active compounds. The focus is usually laid on minimization of hazardous reagents, energy efficiency and renewable feedstock utilization. It provides a critical review of major routes that include their results alongside comparative advantages over the traditional chemical routes and the existing shortcomings and likely trends in this area of study.